Publications

My scientific work has been published in prestigious journals like Journal of the American College of Cardiology, Circulation, and Scientific Reports, contributing to our understanding of genetic influences on cardiovascular health. Additionally, I have extensive experience in reviewing and editing scientific manuscripts across various therapeutic areas, ensuring high-quality scientific communication.

Articles

Effectiveness, safety and discontinuation rates of bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) in people with HIV using real-world data:a systematic review and meta-analysis

Chivite, I.; Berrocal, L.; de Lazzari, E.; Navadeh, S.; Lluís-Ganella, C.; Inciarte, A.; de la Mora, L.; González-Cordón, A.; Martínez-Rebollar, M.; Laguno, M.; Torres, B; Blanco, JL.; Martinez, E.; Mallolas, J.; Ambrosioni, J.
J Antimicrob Chemother. Aug 1;79(8):1775-1783. PMID

Real-world discontinuations due to neuropsychiatric symptoms in people living with HIV treated with second-generation integrase inhibitors: a systematic review

Pérez-Valero, I.: Corona, D.: Martinez, N.; Lopez-Cavanillas, M.; Lluís-Ganella, C.; Luque, I.
Expert Rev Anti Infect Ther. Jun;21(6):655-665. PMID

Weighted Multi-marker Genetic Risk Scores for Incident Coronary Heart Disease among Individuals of African, Latino and East-Asian Ancestry

Iribaren, C.; Lu, M.; Jorgenson, E.; Martínez, M; Lluis-Ganella, C.; Subirana, I.; Salas, E.; Elosua, R.
Sci Rep. 8(1):6853. PMID

Prevalence of genetically confirmed familial hypercholesterolemia in patients with acute coronary syndromes

Amor-Salamanca, A.; Castillo, S.; Gonzalez-Vioque, E.; Dominguez, F.; Quintana, L.; Lluís-Ganella, C.; Escudier, J.M.; Ortega, J.; Lara-Pezzi, E.; Alonso-Pulpon, L.; Garcia-Pavia, P.
J Am Coll Cardiol. 70(14):1732-174

DNA methylation and obesity traits: An epigenome-wide association study. The REGICOR study

Sayols-Baixeras, S.; Subirana, I.; Fernández-Sanlés, A.; Sentí, M.; Lluís-Ganella, C.; Marrugat, J.; Elosua, R.
Epigenetics. 12(10):909-916. PMID

Identification and validation of seven new loci showing differential DNA methylation related to serum lipid profile: an epigenome-wide approach

Sayols-Baixeras, S.; Subirana, I.; Lluís-Ganella, C.; Civeira, F.; Roquer, J.; Do, A.N.; Absher, D.; Cenarro, A.; Muñoz, D.; Soriano-Tárraga, C.; Jiménez-Conde, J.; Ordovas, J.M.; Senti, M.; Aslibekyan, S.; Marrugat, J.; Arnett, D.K.; Elosua, R.
Hum Mol Genet. 28(8):1402. PMID

DNA Methylation and High-Density Lipoprotein Functionality-Brief Report: The REGICOR Study

Sayols-Baixeras, S.; Hernaez, A.; Subirana, I.; Lluís-Ganella, C.; Muñoz, D.; Fitó, M.; Marrugat, J.; Elosua, R.
Arterioscler Thromb Vasc Biol. 37(3):567-569. PMID

Clinical Utility of Multi-marker Genetic Risk Scores for Prediction of Incident Coronary Heart Disease. A Cohort Study among over 51 Thousand Individuals of European Ancestry

Iribarren, C.; Lu, M.; Jorgenson, E.; Martinez, M.; Lluís-Ganella, C.; Subirana, I.; Salas, E.; Elosua, R.
Circ Cardiovasc Genet. 9(6):531-540. PMID

Identification of a new locus and validation of previously reported loci showing differential methylation associated with smoking. The REGICOR study

Sayols-Baixeras, S.; Lluís-Ganella, C.; Subirana, I.; Salas, L.A.; Vilahur, N.; Corella, D.; Muñoz, D.; Segura, A.; Jimenez-Conde, J.; Moran, S.; Soriano-Tárraga, C.; Roquer, J.; Lopez-Farré, A.; Marrugat, J.; Fitó M.; Elosua, R.
Epigenetics. 11(2):174. PMID

Cardiovascular Risk Factors and Ischemic Heart Disease: Is the Confluence of Risk Factors Greater Than the Parts? A Genetic Approach

Elosua, R.; Lluís-Ganella, C.; Subirana, I.; Havulinna, A.; Läll, K.; Lucas, G.; Sayols-Baixeras, S.; Pietilä, A.; Alver, M.; Cabrera,A.; Sentí, M.; Siscovick, D.; Mellander, O.; Fischer, K.; Salomaa, V.; Marrugat, M.
Circ Cardiovasc Genet. 9(3):279-86. PMID

Novel 6p21.3 Risk Haplotype Predisposes to Acute Coronary Syndrome

Sinisalo, J.; Vlachopoulou, E.; Marchesani, M.; Nokelainen, J.; Mäyränpää, MI.; Lappalainen, J.; Paakkanen, R.; Wennerström, A.; Salli, K.; Niemi, HJ.; Männistö, S.; Salo, P.; Junttila, J.; Eskola, M.; Nikus, K.; Arstila, TP.; Perola, M.; Huikuri, H.; Karhunen, PJ.; Kovanen, PT.; Palotie, A.; Havulinna, AS.; Lluís-Ganella, C.; Marrugat, J.; Elosua, R.; Salomaa, V.; Nieminen, MS.; Lokki, ML.
Circ Cardiovasc Genet. 9(1):55-63. PMID

Analysis of gene-gene interactions among common variants in candidate cardiovascular genes in coronary artery disease

Musameh, M.; Wang, W.; Nelson, C.; Lluís-Ganella, C.; Subirana, I.; Elosua, R.; Hall, A.; Kathiresan, S.; Samani, N.; Tomaszewski, M.
PLoS One. 10(2):e0117684. PMID

Association between rs2200733 and rs7193343 genetic variants and atrial fibrillation in a Spanish population, and meta-analysis of previous studies

Ferran, A.; Alegret, JM.; Subirana, I.; Aragonès, G.; Lluís-Ganella, C.; Romero-Menor, C.; Planas, F.; Joven, J.; Elosua, R.
Rev Esp Cardiol (Engl Ed). 67(10):822-9. PMID

Update in Cardiology: Vascular Risk and Cardiac Rehabilitation

Galve, E.; Alegria, E.; Cordero, A.; Facila, L.; Fernandez de Bobadilla, J.; Lluís-Ganella, C.; Mazon, P.; Zarzosa, CP.; Gonzalez-Juanatey, JR.
Rev Esp Cardiol (Engl Ed). 67(3):203-10. PMID

Hypothesis-based Analysis of Gene-Gene Interactions and Risk of Myocardial Infarction

Lucas, G.; Lluís-Ganella, C.; Subirana, I.; Musameh, MD.; Gonzalez, JR.; Nelson, CP.; Sentí, M.; The Myocardial Infarction Genetics Consortium; The Wellcome Trust Case Control Consortium; Schwartz, SM.; Siscovick, D.; O'Donnell, CJ.; Melander, O.; Salomaa, V.; Purcell, S.; Altshuler, D.; Samani, NJ.; Kathiresan, S.; Elosua, R.
PLoS One. 7(8):e41730. PMID

Assessment of the value of a genetic risk score in improving the estimation of coronary risk

Lluís-Ganella, C.; Subirana, I.; Lucas, G.; Tomás, M.; Muñoz, D.; Sentí, M.; Salas, E.; Sala, J.; Ramos, R.; Ordovas, JM.; Marrugat, J.; Elosua, R.
Atherosclerosis. 222(2):456-63. PMID

Post-Genomic Update on a Classical Candidate Gene for Coronary Artery Disease: ESR1

Lucas, G.; Lluís-Ganella, C.; Subirana, I.; Sentí, M.; Willenborg, C.; Musameh, MD.; Schwartz, SM.; O'Donnell, CJ.; Melander, O.; Salomaa, V.; Elosua, R.
Circ Cardiovasc Genet. 4(6):647-54. PMID

Meta-analyses of the association between cytochrome CYP2C19 loss- and gain-of-function polymorphisms and cardiovascular outcomes in patients with coronary artery disease treated with clopidogrel

Zabalza, M.; Subirana, I.; Sala, J.; Lluís-Ganella, C.; Lucas, G.; Tomás, M.; Masiá, R.; Marrugat, J.; Brugada, R.; Elosua, R.
Heart. 98(2):100-8. PMID

Additive Effect of Multiple Genetic Variants on the Risk of Coronary Artery Disease

Lluís-Ganella, C.; Lucas, G.; Subirana, I.; Senti, M.; Jimenez-Conde, J.; Marrugat, J.; Tomas, M.; Elosua, R.
Rev Esp Cardiol. 63(8):925-33. PMID

Qualitative assessment of previous evidence and an updated meta-analysis confirms lack of association between the ESR1 rs2234693 (PvuII) variant and coronary heart disease in men and women

Lluís-Ganella, C.; Lucas, G.; Subirana, I.; Escurriol, V.; Tomas, M.; Senti, M.; Sala, J.; Marrugat, J.; Elosua, R.
Atherosclerosis. 207(2):480-6. PMID

Exact distribution of genetic risk score at the population level

Subirana, I.; Lucas, G.; Esnaola, M.; Lluís-Ganella, C.; Elosua, R.; Gonzalez, JR.
CEB-EIB

Genetic profile of the SCN5A gene in Brugada Syndrome

Coll, M.; Allegue, C.; Pérez-Serra, A.; Picó, F.; Mademont-Soler, I.; Lluís-Ganella, C.; Elosua, R.; Campuzano, O.; Oliva, A.; Partemi, S.; Iglesias, A.; Brugada, R.
Submitted

Evaluation of the role of a genetic risk score for blood pressure on risk of ischemic stroke subtypes

Lucas, G.; Subirana, I.; Lluís-Ganella, C.; Domingues-Montanari, S.; Roquer, J.; Rabionet, R.; Obach, V.; Krupinski, J.; Iniesta, JA.; Martí-Fàbregas, J.; Goyenechea, E.; Jimenez, J.; Elosua, E.
Submitted

Gene-Age Interactions in Blood Pressure Regulation: A Large-Scale Investigation with the CHARGE, Global BPgen, and ICBP Consortia

Simino, J.; Shi, G.; Bis, JC.; Chasman, DI.; Ehret, GB.; Gu, X.; Guo, X.; Hwang, SJ.; Sijbrands, E.; Smith, AV.; Verwoert, GC.; Bragg-Gresham, JL.; Cadby, G.; Chen, P.; Cheng, CY.; Corre, T.; de, Boer, RA.; Goel, A.; Johnson, T.; Khor, CC.; LifeLines Cohort Study; Lluís-Ganella, C.; Luan, J.; Lyytikäinen, LP.; Nolte, IM.; Sim, X.; Sõber, S.; van, der, Most, PJ.; Verweij, N.; Zhao, JH.; Amin, N.; Boerwinkle, E.; Bouchard, C.; Dehghan, A.; Eiriksdottir, G.; Elosua, R.; Franco, OH.; Gieger, C.; Harris, TB.; Hercberg, S.; Hofman, A.; James, AL.; Johnson, AD.; Kähönen, M.; Khaw, KT.; Kutalik, Z.; Larson, MG.; Launer, LJ.; Li, G.; Liu, J.; Liu, K.; Morrison, AC.; Navis, G.; Ong, RT.; Papanicolau, GJ.; Penninx, BW.; Psaty, BM.; Raffel, LJ.; Raitakari, OT.; Rice, K.; Rivadeneira, F.; Rose, LM.; Sanna, S.; Scott, RA.; Siscovick, DS.; Stolk, RP.; Uitterlinden, AG.; Vaidya, D.; van, der, Klauw, MM.; Vasan, RS.; Vithana, EN.; Völker, U.; Völzke, H.; Watkins, H.; Young, TL.; Aung, T.; Bochud, M.; Farrall, M.; Hartman, CA.; Laan, M.; Lakatta, EG.; Lehtimäki, T.; Loos, RJ.; Lucas, G.; Meneton, P.; Palmer, LJ.; Rettig, R.; Snieder, H.; Tai, ES.; Teo, YY.; van, der, Harst, P.; Wareham, NJ.; Wijmenga, C.; Wong, TY.; Fornage, M.; Gudnason, V.; Levy, D.; Palmas, W.; Ridker, PM.; Rotter, JI.; van, Duijn, CM.; Witteman, JC.; Chakravarti, A.; Rao, DC.
Am J Hum Genet. 95(1):24-38. PMID

Book Chapters & Reviews

What is a genetic test and which tipe of information can it provide?

Lluís-Ganella, C.; Marrugat, J.; Elosua, R.
In press

Update in Cardiology: Vascular Risk and Cardiac Rehabilitation

Galve, E.; Alegria, E.; Cordero, A.; Facila, L.; Fernandez de Bobadilla, J.; Lluís-Ganella, C.; Mazon, P.; Zarzosa, CP.; Gonzalez-Juanatey, JR.
Rev Esp Cardiol. pii: S0300-8932(13)00525-3PMID

Pathogenesis of coronary artery disease: focus on genetic risk factors and identification of genetic variants

Sayols-Baixeras, S.; Lluís-Ganella, C.; Lucas, G; Elosua, R.
The Application of Clinical Genetics. 7:15-32PMID

Papel de los factores genéticos y otros biomarcadores en la estimación del riesgo y la prevención cardiovascular

Elosua, R.; Lluís-Ganella, C.; Fitó, M.
Retos actuales en el diagnóstico y manejo del SCA en España, Sociedad Española de CardiologíaPMID

Research Into the Genetic Component of Heart Disease: From Linkage Studies to Genome-Wide Genotyping

Elosua, R.; Lluís-Ganella, C.; Lucas, G.
Rev Esp Cardiol Supl. 9(supl.B)PMID